Biomarker: ApoE
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ApoE
| Description | Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. Apolipoprotein E is associated with age-related risk for Alzheimer's disease and plays critical roles in Abeta homeostasis; the ApoE-ε4 isoform increases risk of Alzheimer's disease. Source |
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| Gene Symbol | APOE Gene |
| Protein Name | Apolipoprotein E Uniprot |
| Synonyms | ApoE; Apolipoprotein E and 7 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
