Biomarker: DNMT3A
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DNMT3A
| Description | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. Source |
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| Gene Symbol | DNMT3A Gene |
| Protein Name | DNA (cytosine-5)-methyltransferase 3A Uniprot |
| Synonyms | DNMT3A; DNA (cytosine-5)-methyltransferase 3A and 6 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
