IGF1R
Description This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.   Source
Gene Symbol IGF1R Gene
Protein Name Insulin-like growth factor 1 receptor Uniprot
Synonyms IGF1R; Insulin-like growth factor 1 receptor and 10 more synonyms used to describe this biomarker that Amplion uses in its algorithms.

Associated Biomarker Indications

Biomarkers sample