Biomarker: IGFBP3
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Description | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Source |
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Gene Symbol | IGFBP3 Gene |
Protein Name | Insulin-like growth factor-binding protein 3 Uniprot |
Synonyms | IGFBP3; Insulin-like growth factor-binding protein 3 and 11 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
