Biomarker: IL17
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Description | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. Source |
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Gene Symbol | IL17A Gene |
Protein Name | Interleukin-17A Uniprot |
Synonyms | IL17; IL17A and 10 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
