Biomarker: IL1 beta
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IL1 beta
| Description | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Source |
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| Gene Symbol | IL1B Gene |
| Protein Name | Interleukin-1 beta Uniprot |
| Synonyms | IL1 beta; IL1B and 14 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
