Biomarker: integrin, alpha X (complement component 3 receptor 4 subunit)

integrin, alpha X (complement component 3 receptor 4 subunit)
Description This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]   Source
Gene Symbol ITGAX Gene
Protein Name integrin alpha-X Uniprot
Synonyms ITGAX; leukocyte adhesion glycoprotein p150,95 alpha chain and 10 more synonyms used to describe this biomarker that Amplion uses in its algorithms.

Associated Biomarker Indications

Biomarkers sample