Biomarker: Paraoxonase 1
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Paraoxonase 1
| Description | The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. Source |
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| Gene Symbol | PON1 Gene |
| Protein Name | Serum paraoxonase/arylesterase 1 Uniprot |
| Synonyms | Paraoxonase 1; PON1 and 16 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
