Biomarker: COX2
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COX2
| Description | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. Source |
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| Gene Symbol | PTGS2 Gene |
| Protein Name | Prostaglandin G/H synthase 2 Uniprot |
| Synonyms | COX2; PTGS2 and 14 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
