Biomarker: Thyroid stimulating hormone, beta
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Thyroid stimulating hormone, beta
| Description | The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. Source |
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| Gene Symbol | TSHB Gene |
| Protein Name | Thyrotropin subunit beta Uniprot |
| Synonyms | Thyroid Stimulating Hormone; Thyroid stimulating hormone, beta and 8 more synonyms used to describe this biomarker that Amplion uses in its algorithms. |
Associated Biomarker Indications
